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Respondents Show Vivid Interest in Developing Clinical NGS-based Tests for Infectious Disease Testing Applications
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The primary goal of this research is to analyze the current and future adoption plans of Next-Generation Sequencing (NGS) for clinical applications. The survey seeks to collect the following key information:• Outsourcing needs and clinical NGS service providers• Current and future interest areas of clinical NGS• Genetic elements of interest• Purchase patterns for instruments and reagents• Predominantly used clinical methods (e.g., chip sequencing, whole exome)• Perspectives of NGS used as complement or replacement for current methods• Platforms used for NGS clinical data interpretation• Predominantly cited instruments for clinical use• Familiarity with clinical NGS service providers• Factors promoting adoption• Factors limiting adoption• Best practices from labs—direct quotes from lab managersResearch MethodologyLab managers of clinical labs were invited to participate in an online survey during August–November 2016. To qualify for survey participation, respondents had to be working in a private or public laboratory, clinical research institution, reference laboratory, academic medical center facility, hospital lab, or diagnostic company that employs NGS for clinical use. Respondents had to be constant users of this technology, belong to the scientific community, and be in a position to authorize purchases. Over 184 respondents qualified for the survey including C-level officers, lab managers, directors, physicians, post docs, and principal investigators that had a direct interference with the clinical NGS community. End users were also evaluated for their ability to authorize purchases or make product recommendations. Respondents indicated a wide range of job titles, such as lab directors, scientists, lab managers, clinicians, pathologists, and lab technicians. In total, about 82% of respondents work in the United States. Nevertheless, this study is considered global because the survey was open to respondents from all countries.
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