Proteomics: Promising Research/Potential Applications/and New Developments (Technical Insights)
Proteomics: Promising Research/Potential Applications/and New Developments (Technical Insights)
RELEASE DATE
10-Oct-2001
10-Oct-2001
REGION
Global
Global
Research Code: D232-01-00-00-00
SKU: HC01295-GL-TR_05570
$3,950.00
Special Price $2,962.50 save 25 %
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SKU
HC01295-GL-TR_05570
Description
To achieve the promise presented by mapping the human genome, we must strive to understand what is happening in a cell beyond the DNA sequence of a given gene. As a result scientists are performing extensive study of proteins. While genes carry the blueprints for life, proteins perform the vital functions necessary for life to exist. This report provides in-depth coverage of proteomic research and identifies the most promising developments and potential applications.
Table of Contents
Genes and Proteins
- Genomics and Proteomics
- Bioinformatics Analysis of Proteomics Data
- Pharmaceutical Applications
Proteomics Techniques
- Proteomics Analysis
- 2-D Gel Electrophoresis
- Spectrometry
- Phage Display
- Yeast 2-Hybrid System
- Lab on a Chip (LOC) Technologies
- Microfluidic LOCs
- Biochips and Microarrays
- Additional Proteomics Technologies: Bioinformatics; Functional Genomics; and Structural Genomics
Introduction
Bioinformatics Analysis of Proteomics Data
- Introduction
- Proteomic Methods
Pharmaceutical Applications
- Bioinformatics Analysis of Proteomics Data
- Studying Proteins Versus Studying Genes
Proteomics Techniques
- Identifying Novel Therapeutics
- Drug Discovery
Phage Display; Yeast 2-Hybrid System
- Proteomics Techniques
- 2-D Gel Electrophoresis
- Spectrometry
Lab-on-a-Chip (LOC) Technologies
- Phage Display
- Yeast 2-Hybrid System
Cal Tech's Beckman Institute: MRI Shows Gene Expression Anywhere in Organism
GeneProt: New Method Automates Mass Spec
University of Michigan: New Protein Separation Faster Than 2-D Gels
Cytogen: Ligand Target Cloning
Hybrigenics
Lexicon: Gene-Trapping Technique Detects Rare Proteins
RheoGene: Multiplexed Gene -Regulation Technology for Studying Complex Gene Interactions
- Cal Tech's Beckman Institute: MRI Shows Gene Expression Anywhere in Organism
HTS Biosystems: Surface Plasmon Resonance
- GeneProt: New Method Automates Mass Spec
Rosemount: Mass Spectrometer on a Chip
- University of Michigan: New Protein Separation Faster Than 2-D Gels
Caliper Technologies: Microfluidics and Lab on a Chip
- Cytogen: Ligand Target Cloning
Johns Hopkins; NYU; Mount Sinai: Bisubstrates Squelch Errant Enzymes
- With Institut Pasteur: Hybrigenics Named Exclusive Licensee To Protein-Interactions Patent
- Bacterial Two-Hybrid System Better Than Yeast
- Protein Interactions Mapped out in H. pylori
- Map of Protein Interactions Between HIV and Host Cells
- With Lynx Therapeutics: Obesity
- With XTL: Hepatitis C Virus (HCV) Therapeutics
SUNY and University of Tokyo: Making Novel Proteins Using a 21st-Century Amino Acid
- Lexicon: Gene-Trapping Technique Detects Rare Proteins
Vanderbilt University: New Technology Expands Molecular Photography Options
- RheoGene: Multiplexed Gene -Regulation Technology for Studying Complex Gene Interactions
Virginia Tech: Dried Cells; Tissues Could Solve Biological Materials Storage; Transport Problems
- HTS Biosystems: Surface Plasmon Resonance
- With Dyax Corp: Phage Display for Antibody Chips
- With Boston Probes and Applied Biosystems: Peptide Nucleic Acid (PNA) Technology
- Mitsubishi Chemical: Purchase and Distribution Agreement
Whitehead Institute and Mass General: Interaction Sequence Tags
- Rosemount: Mass Spectrometer on a Chip
Phylos
- With Structural Genomix: High-Throughput Protein Analysis
- Conflict with Aclara Resolved
Harvard University: Protein Chips Probe Protein Function
- Johns Hopkins; NYU; Mount Sinai: Bisubstrates Squelch Errant Enzymes
University of Pennsylvania: IDAT Detects Proteins at Unprecedented Resolution
- SUNY and University of Tokyo: Making Novel Proteins Using a 21st-Century Amino Acid
Caliper and Structural Genomix High Throughput Proteomics Labchip
- Vanderbilt University: New Technology Expands Molecular Photography Options
Detection on a Chip: Microphotonics
- Virginia Tech: Dried Cells; Tissues Could Solve Biological Materials Storage; Transport Problems
Hoffman-La Roche: Bacteria Chips to Study Antibiotics
- Whitehead Institute and Mass General: Interaction Sequence Tags
EMBL Begets Cellzome: TAP Method Yields Low-Abundance Proteins and Multicomponent Complexes
- Alternative to Phage Display
- Protein-Expression Chip
- Antibody-Like Protein Scaffolds for Cancer Treatment
NEN Life Science: Analyzing Gene Expression or Copy Number on a Chip
- Harvard University: Protein Chips Probe Protein Function
Functional Genomics
Human Genome Sciences Wins AIDS-Receptor Drug Target Patent
Agritope: Functional Genomics for Plants
Devgen NV: Belgian Firm Focuses on Functional Genomics
Paradigm Genetics: 150 Plant Gene Functions per Week
CuraGen: Functional Genomics for Therapeutics
Rigel and Pfizer: Allergies
DOE Grants Focus on Microbial Waste Remediation; Carbon Management; Energy Production; Biotech
Genset: Protein Takes Fat off Obese Mice
MDS Proteomics Links with Zyomyx; IBM
Arqule and Acadia: G-Protein-Receptors as Drug Targets
Neotherapeutics: Therapies for Neurodegenerative Disease
Neogene Technologies: G-Protein-Coupled Receptors
Cereon Genomics: Arabidopsis Data Released through Public-Private Partnership
Exelixis: Functional Genomics in Drosophila
Aurora Patents Gene Tagging System
UPenn: Pure-Blood Microchips
Cadus Pharmaceutical: Orphan Receptors and G-Protein
Mycota Biosciences: Functional Genomics in Fungus to Find Drug Targets
Mendel Biotech: Technology Makes Plants More Weatherproof
Hyseq Protein May Reduce Blood Clotting
Structural Genomics
Protein Folding
NIGMS: $150 Million for Multicenter Protein Structure Initiative
University of Washington: Computational Method may Hold Key to Predicting Protein Folding
Berkeley Lab's Advanced Light Source Accelerates X-Ray Crystallography
University of California-Santa Cruz: New Images Reveal the Workings of Cellular Protein Factories
Keio University; Teikyo University Biotechnology Center: Snapshots of a Molecular Motor
Integrative Proteomics: X-Ray; NMR; Mass Spec for Target ID
Wistar Institute: X-Ray Structure Reveals Similarities in Molecules Linked to Cancers
NIAID; St. Jude's; St. Andrews: Advance in Tackling Common Viral Respiratory Disease
Structural Bioinformatics Patents NMR 3-D Structure Technology
Bioinformatics and Computational Proteomics
Incyte Genomics
Turbogenomics: Turbo-Charged Blast Sequence Comparison
Celera Genomics: Now Proteomics
Entigen Provides Services to Smaller Research Groups
GeneData AG: Collaboration Targets Antibacterials
Alphagene Identifies 264 New Genes
Lion Bioscience Provides System to Nestle and Bayer
Geneformatics: Protein Structure Prediction
Proteome and Spotfire: Databases and Analytic Software
Netgenics
Shanghai Genecore: Complicated Genealogy
Norwegian Radium Hospital: Mining the Biobibliome
National Center for Genome Resources: ISYS Integrates Bioinformatics Tools; Databases
McGill University Launches Centre for Bioinformatics
Compugen and UCSF: New Chemokine Binds HIV Co-Receptors
Millennium Pharmaceuticals
ZymoGenetics Runs the Gamut of Protein R&D
Proteome Systems: Australians Build Proteomics Capabilities
Gemini Genomics and Large Scale Biology Corp. Isolate 70 Disease Proteins
Myriad Genetics
Eos Uses Morphosys Combinatorial Antibody Library
MitoKor: Alzheimer's Disease
Oxford Glycosciences
Sunesis Pharmaceuticals
Morphochem AG
Scriptgen Becomes Anadys and Expands
Fraunhofer Institute Pinpoints Candida Pathogenicity Proteins
Genetrace Systems Acquires Strata Biosciences
Axcell Maps Interactions Of WW Domain Proteins
Large Scale Biology Corp.; Navy; NIH Look for Stem-Cell Factors
Syngenta and Myriad: Rice Proteomics May Mean Better Cereal Crops
Ciphergen Biosystems: Biomarkers
Beyond Proteomics: Glycomics
UPenn Scientists Show How Chaperonins Catch Protein-Folding Errors
Newcastle University: Fragments of Dinosaur Protein can Survive in Bone Fossils
Scripps: Expanding E. Coli's Amino Acid Repertoire Paves Way for Engineered Proteins
Gladstone Institute; UCSF: HIV Viral Protein Plays Offense and Defense Against Immune System
UCSD: Protein Responsible for Failing Heart
Ceres Pharmaceuticals: Powerful New Vaccines from Yeast
Cellular Signaling Alliance Unites Researchers Via Internet
University of Illinois: New Mechanism for Cell Signaling
NCI Intensifies Informatics
Xenometrix Wins US Gene-Profiling Patent
PNNL: Top Role in Biological Sciences Initiative
Dana-Farber Cancer Institute: Molecular Gateways to Death
Markets
Barriers to Commercialization
Appendix A: Contacts
Appendix B: Recent Patents in Proteomics and Bioinformatics
Appendix C and D: Website URLs and Publications
To achieve the promise presented by mapping the human genome, we must strive to understand what is happening in a cell beyond the DNA sequence of a given gene. As a result scientists are performing extensive study of proteins. While genes carry the blueprints for life, proteins perform the vital functions necessary for life to exist. This report provides in-depth coverage of proteomic research and identifies the most promising developments and potential applications.
No Index | Yes |
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Podcast | No |
Industries | Healthcare |
WIP Number | D232-01-00-00-00 |
Is Prebook | No |