Introduction

• Introduction
• Technology Primer

Scope and Methodology

• Scope
• Methodology

Application Analysis and Trends

Industry Trends and Assessment

• Microbial Fermentation
• Glycomics and Biopharmaceuticals
• Diagnostic Applications
• Therapeutic Applications
• Biopolymers
• Cell Culture
• Sensors in Biotechnology Processing
• Other Applications

Antibodies

Vaccines

Antibiotics

• Enhanced Genetic Evolution--USA
• Phage Display and Humanized Antibodies--USA
• RNA Synthesis and Delivery of Antibodies--USA
• Humanized Antibodies from Yeast--USA
• Comparing Polyclonal Humanized Antibodies with Monoclonals--USA
• High-Throughput High-Diversity Generation of Antibody Platform--UK
• Fucose Increases Antibody-Dependent Cellular Cytotoxicity--Japan
• Production of Fully Human Antibodies through Human Combinatorial Antibody Libraries--Germany
• Phage Display Technique Targets Bacterial Haptens--UK
• Other Companies

Other Biopharmaceuticals

• Flu Vaccine from Cell Culture Instead of Eggs--USA
• Potato Vaccine for Hepatitis B--USA

Enzymes

• Antimicrobial Peptide from Fungus Kills Resistant Infections--Denmark
• Metabolic Pathway Engineering Simplifies Antibiotic Preparation--Netherlands

Plants and Algae

• Improved Recombinant Interferon--USA
• Bioconversion for Production of Chiral Compounds--Japan
• Biocatalysis and Metabolic Engineering for Vitamin and Nutrient Production--Germany
• Modified E. Coli Make Human Glycoproteins--USA

Transgenic Animals

• Fungal Genome Sequence for Better Enzymes--USA
• Directed Evolution: Increased Mutation Rate Yields Enhanced Enzymes--USA
• Solid-Phase Massively-Parallel Screening System for Improved Enzyme Mutants--USA
• Rearranging DNA to Improve Variants--USA
• Genetic Engineering to Boost Xylanase Output--Canada

Biopolymers

• Lack of Financing Shuts down Large-Scale Biology--USA
• Transgenic Duckweed for Protein Manufacture--USA
• Tobacco Plant-Based Monoclonal Antibodies against Tumor Cells--USA
• Cotton Roots Produce Gossypol Antibiotic--USA
• Metabolomics Changes Plants to Chemical Factories--USA
• Insulin Production in Plants--Canada
• Polysaccharide from Immobilized Callus Cultures--India

Bioreactors and Fermenters

• Human Antibodies and Other Therapeutic Proteins from Chicken Eggs--USA
• Transgenic Mice for Production of Fully Human Antibodies--USA
• Human Antithrombin from Transgenic Goat Milk--USA
• Transgenic Rabbits Produce C1 Inhibitor for Hereditary Angioedema--Spain

Cell Culture

• Stabilized Gene Transfer for Producing Recombinant PHA--USA
• Yeast Produces Tailor-Made PHA Polymers--USA
• Limiting Nitrogen Boosts Bacterial PHA Synthesis--Ireland

Sensors and Detectors

• Eliminating Cryptic Plasmid Improves Fermentation--USA
• Microreactor Regenerates Enzyme Cofactors--USA
• Boost Cobalamin to Improve Fermentation Microbes--USA
• Novel Two-Phase Fermenter Process--Netherlands
• Tubular versus Bubble Column Photobioreactors--Spain

Nucleic Acid Purification

Chromatography

Membrane and Filter Separations

Manufacture and Scale-Up

Process Design and Management Software

Technology Development Restraints And Market Challenges

Technology Adoption Drivers and Benefits

Patents

Key Industry Participants

Technology Leadership Award

Technology Innovation Award

Excellence in Technology Award

Database Tables