Innovations in RNA Interference and MicroRNA Therapies

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This Drug Discovery TechVision Opportunity Engine (TOE) depicts new life sciences trends across RNA targeting technologies, such as RNA interference and microRNA therapies, aiming for accelerating drug discovery and development. The power of ‘druggable’ RNA propelling therapeutics discovery pathway is analyzed in-depth through notable innovations in microRNA-based platforms, self-delivered RNA interference-based liposomes, anti-code therapeutics, therapeutic ribonucleases, antisense drugs, RNA splicing modulation, exon skipping treatments, and microRNA programming. The corresponding clinical trial scenario involving RNA-based treatments is also depicted.The Drug Discovery TechVision Opportunity Engine (TOE)

Table of Contents

Innovations in RNA Interference and MicroRNA TherapiesThe Power of ‘Druggable’ RNA Accelerating Therapeutics Discovery Pathway Novel MicroRNA-based Platform to Accelerate Drug Discovery and DevelopmentSelf-delivering RNA Interference-based Liposomes as Next-generation TherapeuticsShort Interfering RNA Molecules as Therapeutic Anti-code CandidatesTherapeutic Ribonucleases Directly Targeting transfer-RNA and Precursor micro-RNARNAi Therapeutic Awaiting NDA Approval for Hereditary AmyloidoisisSecond Generation Antisense Drug for Treatment of Hereditary AmyloidosisModulating RNA Splicing as a Treatment for CancerExon Skipping Treatment by PMO TherapeuticsmRNA Drug ProgrammingDrug DiscoveryTechnology Focus and Trends Clinical Trial AnalysisClinical Trial Analysis (continued)Industry InteractionsIndustry Interactions (continued)

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