Market participants in the South African Healthcare Industry was interviewed to identify the challenges in the pharmaceutical and medical devices industries as well as the future opportunities for these companies. In understanding these dynamics, the market for medical imaging, patient monitoring, branded and generic pharmaceuticals were quantified and growth forecasts were calculated for 2008 to 2014. Drivers, restraints, and industry challenges as well as market shares of key participants were established A thorough strengths, weaknesses, opportunities, and threats (SWOT) analysis was conducted.