Impact of genome editing techniques

Breakthrough innovations across agriculture and human therapeutics

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Improvements and new gene editing techniques are constantly that have a high disruptive and revolutionary impact within the application for healthcare and other verticals. Accurate and highly precise manners of manipulating genetic content has not been present until the recent developments across the space of gene editing techniques. These tools, that have been developed can effectively provide researchers with the capacity to understand disease and potentially cure it. It also has the potential to impact the production rate and quality of agricultural and livestock products.

Recent developments across genome editing technologies have resulted in the creation of next generation nucleases, that have higher levels of accuracy when correcting genetic mutations and defects. The classes under the genome editing technologies are the 4 broad families of nucleases: ZFNs, TALENs, CRISPR/Cas9, and Meganucleases. Though there are non-nuclease-based approaches and various proprietary gene editing techniques, the industry favorites are still the nuclease-based approaches.

Gene editing technologies have an impact across multiple applications areas including plant and animal genetic engineering. However, the area of most disruption is across human cell line engineering, which enables the development of next generations therapies and drugs. However, the agricultural industry has seen more success with gene editing techniques largely due to the less stringent regulatory environment.

From a regional standpoint, the United States of America, has currently contributed the most toward the development of these unique and highly beneficial techniques. While Europe and Asia are closely following with increased investments entering these regions through partnership agreements.

Table of Contents

Executive SummaryResearch ScopeSneak Peak–Gene editing Where does gene editing stand today? Segmentation–Application Overview Segmentation–Technology overview Technology OverviewMain technology areas of focus enabling gene editing Other technologies enabling gene editing Technology capability Technology capability : Comparative assessment Approach : Technology Readiness Level (TRL) TRL: ZFNsTRL: TALENsTRL: CRISPR/Cas9Industry Initiatives and Market Impact Market Impact of Technology/Business AcceleratorsMarket Impact of Technology/Business ChallengesInnovation Ecosystem: Key InnovatorsAgriculture–Plant-based applications Player assessment across applicationBreakthrough’s using gene editing technologies Industrial bio-based applications Player assessment across applicationBreakthrough’s using gene editing technologiesGene edited animal-based applications Player assessment across applicationBreakthrough’s using gene editing technologiesHuman therapeutics applications Player assessment across applicationUtilization of Gene editing Breakthrough’s using gene editing technologies Breakthrough’s using gene editing technologiesStakeholder Assessment Stakeholder Assessment (continued) Stakeholder Assessment (continued) Stakeholder assessment Stakeholder assessment (continued)Stakeholder assessment (continued)Partnership Assessment Partnership Assessment Partnership Assessment Partnership Assessment Opportunity Assessment and Technology Roadmap Approach–Company Profile Editas Medicine Intellia Therapeutics CRISPR Therapeutics CaribouRegulatory Landscape Geographic Assessment Technology RoadmapPatent AnalysisPatent search ScopePatent Publishing Trends, Global, 2010–15*Top 20 Patent holders, Global, 2010- 15*Patents per Source Jurisdiction (Top 10 Patent offices), Global, 2010–15*Key ContactsKey ContactsLegal DisclaimerThe Frost & Sullivan StoryThe Frost & Sullivan StoryValue Proposition: Future of Your Company & CareerGlobal PerspectiveIndustry Convergence360º Research PerspectiveImplementation ExcellenceOur Blue Ocean Strategy




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genome editing market
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genome editing technology
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genome editing market

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