Why Is It Increasingly Difficult to Grow?The Strategic Imperative 8™: Factors Creating Pressure on Growth

The Strategic Imperative 8™

The Impact of the Top 3 Strategic Imperatives on the Structural Heart Implants Industry

Growth Opportunities Fuel the Growth Pipeline Engine™

Research Methodology

SHD Overview

Most Prevalent

Most Well-established Interventional Technique for Valvular Heart Disease: Percutaneous Mitral Valvuloplasty (PTMV)

PTMV is the Most Well-established Structural Interventional Technique (continued)

PTMV is the Most Well-established Structural Interventional Technique (continued)

Structural Heart Implants Segmentation

Interventional Treatment—Mainly for Patients at Surgical Risk

Market Analysis of Technologies

Market Analysis of Technologies (continued)

Market Analysis of Technologies (continued)

Market Analysis of Technologies (continued)

Market Analysis of Technologies (continued)

Growth Drivers

Growth Restraints

Scope of Analysis

Preference to Mitral Valve Repair over Mitral Valve Replacement

Mitral Valve Material Analysis

Mitral Valve Material Analysis (continued)

Self-expanding Frame of the Valves Generally Comprises Nitinol

Most-adopted Design Intervention—Trileaflet Valve Comprising Pericardium in a Self-expanding Nitinol Frame

Most-adopted Design Intervention—Trileaflet Valve Comprising Pericardium in a Self-expanding Nitinol Frame (continued)

United States Has the Most Innovations in TMVr/TMVR

Tc-ASD can Treat ASD of Septum Secundum

ASD Material Analysis—Nitinol Wireframes Causing Erosion in Implanted Tc-ASD Devices

ASD Material Analysis—Nitinol Wireframes Causing Erosion in Implanted Tc-ASD Devices (continued)

Flexible Petal Design Ensures Less Friction Minimizing the Erosion

Gore Medical Tc-ASDs are FDA Approved and are the Most Successful

Tc-ASDs Geographical Analysis—United States Has the Most Innovations Dealing with Tc-ASDs

AI-enabled Prosthetic Mitral Valves as the Future of TMVR/TMVr

3D-bio-printed, Bio-inspired ASD Occluder is the Future

Structural Heart Implants for MIS

Need for Balancing Innovation and Regulation

Patent Database Analysis for TMVR/TMVr Industry

Patent Database Analysis for ASD Closure Devices

Emerging technology Analysis for Mitral Implants and ASD Occluders

Application of AI in Cardiovascular Implants in the Growth Phase

Growth Opportunity 1: Bio-inspired or Biomimetic Structural Heart Implants will Lead to Less Device Failure

Growth Opportunity 1: Bio-inspired or Biomimetic Structural Heart Implants will Lead to Less Device Failure (continued)

Growth Opportunity 2: Microelectronics and AI-enabled Smart Implants for Capturing Real-time Heart Parameters

Growth Opportunity 2: Microelectronics and AI-enabled Smart Implants for Capturing Real-time Heart Parameters (continued)

Growth Opportunity 3: Collaborative/In-house Development of Visualization Techniques with Cardiac Implants

Growth Opportunity 3: Collaborative/In-house Development of Visualization Techniques with Cardiac Implants (continued)

The Latest Patents Include AI and ML-enabled Intelligent Structural Heart Implants

Technology Readiness Levels (TRL): Explanation

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