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Developments in miRNA sequencing and analysis are driving future growth potential in therapeutics and diagnostics
29-Aug-2022
Global
Technology Research
DA64-01-00-00-00
HC03580-GL-TR_26854
Accelerated research around RNA-based therapeutics and diagnostics, accompanied by technology advancements in sequencing the human genome, has resulted in a better understanding of the role of miRNA in biological pathways, enhancing its potential in both therapeutics and diagnostics. The successful clinical validation of miRNA diagnostic tests has created several opportunities for miRNA diagnostic companies. The role of miRNAs as circulating biomarkers makes it possible to perform diagnostics from body fluids. The potential of miRNA biomarkers in identifying diseases like thyroid cancer, breast cancer, and ovarian cancer is being explored. miRNA diagnostics is expected to grow further and become prominent in point-of-care diagnostics. The development of miRNA therapeutics has had its challenges with respect to stability and delivery issues. However, newer approaches in the development of antagomiRs (miRNA inhibiting drugs) and agomiRs (miRNA replacement therapy) have shown promising results. miRNA companies have witnessed a highly competitive ecosystem and have been acquired by several larger pharma and diagnostics companies upon their entry into the clinical trial stage.
This study focuses on the developments in miRNA therapeutics and diagnostics. It identifies the factors driving interest in miRNA research as well as those affecting the commercialization of miRNA therapeutics and diagnostics. The report also discusses the emerging opportunities for miRNA technology companies and highlights investment prospects for industry participants and stakeholders.
Why Is It Increasingly Difficult to Grow?The Strategic Imperative 8™: Factors Creating Pressure on miRNA Technology Growth
The Strategic Imperative 8™
The Impact of the Top 3 Strategic Imperatives on the Micro Ribonucleic Acid (miRNA) Industry
Growth Opportunities Fuel the Growth Pipeline Engine™
Research Methodology
Scope of Analysis
Segmentation
Growth Drivers
Growth Restraints
Emerging Trends in miRNA Therapeutics and Diagnostics
Increasing Research in miRNA Therapeutics and Diagnostics
miRNA Drugs Experiencing Rapid Strides in Clinical Development
Enablers Accelerating miRNA Research and Commercial Development
Introduction to miRNA Therapeutics
miRNA Therapeutics to Address Complex Diseases
Evolving Approaches in Developing Antagomirs and miRNA Mimics
Structural Modifications to Increase miRNA Stability
Application of miRNAs in Diseases
Oncology
Respiratory Diseases
Neurology
Cardiovascular Diseases
Other Diseases
Other Diseases
miRNA Therapeutics in Development by Companies
Increasing miRNA Research Activities in Academia
Challenges in miRNA Therapeutics
Important miRNA Therapeutics Delivery Systems
Comparison of miRNA Delivery Systems
Developing Newer Delivery Systems
Future Prospects of miRNA Therapeutics
Introduction to miRNA Diagnostics
Benefits of miRNA Diagnostics
Opportunities for Using miRNA in Diagnostics
Emerging Developments in miRNA Diagnostics
Oncology
Neurological Diseases
Cardiovascular and Other Diseases
M&A miRNA Therapeutics
M&A miRNA Diagnostics
Funding Landscape of miRNA companies
miRNA—Important Takeaways
miRNA—Important Takeaways
Growth Opportunity 1: Improved Targeted Delivery Systems to Reduce Off-target Effects and Toxicity
Growth Opportunity 1: Improved Targeted Delivery Systems to Reduce Off-target Effects and Toxicity (continued)
Growth Opportunity 2:Development of POC Diagnostics to Detect Circulating Biomarkers Across Diseases
Growth Opportunity 2: Development of POC Diagnostics to Detect Circulating Biomarkers Across Diseases (continued)
Growth Opportunity 3: Companion Diagnostics for Precision Medicine
Growth Opportunity 3: Companion Diagnostics for Precision Medicine (continued)
Technology Readiness Levels (TRL): Explanation
Funding Landscape for miRNA Therapeutics
Funding Landscape for miRNA Therapeutics (continued)
Funding Landscape for miRNA Diagnostics
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| Deliverable Type | Technology Research |
|---|---|
| Author | Neeraja Vettekudath |
| Industries | Healthcare |
| No Index | No |
| Is Prebook | No |
| Keyword 1 | mirna microrna |
| Keyword 2 | microrna companies |
| Keyword 3 | rna mirna |
| Podcast | No |
| WIP Number | DA64-01-00-00-00 |
Advancements in miRNA: Technology Assessment
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