The manufacturing and production industry is set for radical transformation spurred by 5 key forces (the cloud, Big Data, analytics, virtualization, and the Internet of Things). These technologies will sustain the future manufacturing community and ensure sustainable growth and profitability. This study investigates the impact of these forces on process industries (oil and gas, chemicals, pharmaceuticals, and mining and power) and analyzes how their overlap will serve smart plants through integrated solutions. Chapters follow a first, second, and third base format: 1. Business Insight (understanding the industry), 2. Growth Insight (understanding opportunity), and 3. Profit Insight (understanding strategies). The base year is 2013.