Innovation Waves in Immuno-oncology Therapy Development

Innovation Waves in Immuno-oncology Therapy Development

Next-gen Cell Therapies and Precision Immunotherapies are Driving Growth and New Product Development

RELEASE DATE
12-Feb-2024
REGION
Global
Deliverable Type
Market Research
Research Code: DAA2-01-00-00-00
SKU: CM_2024_582
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$4,950.00
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SKU
CM_2024_582

Innovation Waves in Immuno-oncology Therapy Development
Published on: 12-Feb-2024 | SKU: CM_2024_582

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Immuno-oncology (I-O) therapies target tumors by harnessing the host’s immune system. With the growing incidence and prevalence of various types of aggressive and refractory cancers, the next-generation I-O therapy pipeline has witnessed significant growth. Chimeric antigen receptor (CAR)-T cell therapy and tumor-targeted antibody therapies, including monoclonals, antibody-drug conjugates (ADCs), bispecific antibodies, and several therapeutic cancer vaccines, are making rapid strides in clinical trials as effective immunotherapy. This study discusses the key trends and technologies driving the development of such I-O therapies. It delves into advancements in cancer vaccines and cell therapies for various cancer indications, highlighting some of the innovators in this space. Next-generation cell therapies, personalized cancer vaccines, and strategic areas of focus have also been discussed in this report. The study examines the factors driving and restraining this industry and identifies the growth opportunities emerging from the changes in this space for market players and stakeholders to leverage.

Key questions answered in this study:

•     What does the current clinical landscape of I-O therapies look like?
•     Which are the technology enablers driving the adoption of I-O therapies?
•     What are the key developments in adoptive cell therapies and cancer vaccines?
•     What are the roadblocks to successful translation?
•     What are the research and development (R&D) focus areas?
•     What are the key focus areas for the future?

Why Is It Increasingly Difficult to Grow?The strategic imperative 8™: Factors creating pressure on growth

The Strategic Imperative 8™

The Impact of the Top 3 Strategic Imperatives on the Immuno-Oncology (I-O) Therapeutics Industry

Growth Opportunities Fuel the Growth Pipeline Engine™

Research Methodology

Need for Immunotherapy

Scope of Analysis

Segmentation: Snapshot of I-O Therapies

I-O Therapies in Development

I-O Therapies in Development (continued)

Growth Opportunities in I-O Therapy

Growth Drivers

Growth Restraints

I-O Technology Trends and Developments

Trends in I-O Therapeutics

Therapeutic Development Trends in I-O

R&D Focus Areas to Boost Immunotherapies

Modulation of TME: Solid Tumor Type Determines Therapy

Developing Effective Preclinical Models for Translation

Stakeholders Developing Preclinical Models for I-O Therapy Evaluation

Holistic Tumor Profiling to Boost Precision Oncology Efforts

Quick Facts on I-O Therapies

Clinical Development Landscape of I-O Therapies

Cell Therapy to Create the Next Wave of I-O Developments

Cell Therapy Types: Snapshot

Clinical Development Landscape of I-O Cell Therapies

Emerging Areas of Focus to Improve Functionality and Safety Cell Therapies

Next-generation CAR-T Therapy Development

Priority Areas to Improve the Accessibility of Cell Immunotherapy

Innovative Technologies for Cell Therapy Manufacturing and Delivery

Stakeholders Developing Emerging Next-gen Cell Therapies

Stakeholders Developing Emerging Next-en Cell Therapies (continued)

Potential of Vaccines to Address Challenges with Difficult-to-Treat Cancers

Cancer Vaccine Types

Personalized Neoantigen Vaccines in Clinical Development

Personalized Neoantigen Vaccines in Clinical Development (continued)

Areas of Focus to Bolster Cancer Vaccine Development

RNA Vaccines to Drive the Wave of Prophylactic and Therapeutic Cancer Vaccines

Road Ahead for Cancer Vaccines and Immunotherapy

Emerging Cancer Vaccine

Impact of Emerging Cancer Vaccines Across Cancers

Regional Trends in I-O Developments and Adoption

Federal Initiatives and Programs Driving I-O Therapy Development

I-O Deals and Investment Trends

Notable Partnerships and Collaborations in I-O, 2023

I-O: Current Gaps and Potential Opportunities

Strategies to Improve Access and Care Delivery of I-O Therapies

Growth Opportunity 1: Combination Immunotherapies

Growth Opportunity 1: Combination Immunotherapies (continued)

Growth Opportunity 2: Precision Oncology

Growth Opportunity 2: Precision Oncology (continued)

Growth Opportunity 3: Advanced Synthetic Biology Platforms

Growth Opportunity 3: Advanced Synthetic Biology Platforms (continued)

Growth Opportunity 4: Organoids and Organ-on-Chip Models

Growth Opportunity 4: Organoids and Organ-on-Chip Models (continued)

List of a Few Approved ADCs

Approved CAR-T Therapies (global)

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Immuno-oncology (I-O) therapies target tumors by harnessing the host s immune system. With the growing incidence and prevalence of various types of aggressive and refractory cancers, the next-generation I-O therapy pipeline has witnessed significant growth. Chimeric antigen receptor (CAR)-T cell therapy and tumor-targeted antibody therapies, including monoclonals, antibody-drug conjugates (ADCs), bispecific antibodies, and several therapeutic cancer vaccines, are making rapid strides in clinical trials as effective immunotherapy. This study discusses the key trends and technologies driving the development of such I-O therapies. It delves into advancements in cancer vaccines and cell therapies for various cancer indications, highlighting some of the innovators in this space. Next-generation cell therapies, personalized cancer vaccines, and strategic areas of focus have also been discussed in this report. The study examines the factors driving and restraining this industry and identifies the growth opportunities emerging from the changes in this space for market players and stakeholders to leverage. Key questions answered in this study: What does the current clinical landscape of I-O therapies look like? Which are the technology enablers driving the adoption of I-O therapies? What are the key developments in adoptive cell therapies and cancer vaccines? What are the roadblocks to successful translation? What are the research and development (R&D) focus areas? What are the key focus areas for the future?
More Information
Deliverable Type Market Research
Author Rruplekha Choudhurie
Industries Chemicals and Materials
No Index No
Is Prebook No
Keyword 1 Immuno-Oncology Industry Insights
Keyword 2 Therapy Development Dynamics
Keyword 3 Immuno-Oncology Market Analysis
Podcast No
WIP Number DAA2-01-00-00-00